ACOMPLIA
INFORMATION
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This
FAQ is for information only, and has been compiled from a number
of sources to give an overview of the use and effects of Acomplia.
It is not a definitive guide to the effects or implications of use
of Acomplia, nor is it intended replace the advice of qualified
healthcare professionals. If you have any concerns about the use
of Acomplia or any possible side-effects, consult your healthcare
provider.
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This new treatment works by blocking endogenous cannabinoid binding to neuronal CB1 receptors.
Activation of these receptors by endoegenous cannabinoids, such as anadamide, increases appetite.
It is the only endocannabinoid receptor antagonist in clinical development and thus offers a unique therapeutic
approach to appetite control and weight reduction.
The drug also has potential as a treatment for smoking cessation because the endocannabinoid system
is involved in the body's response to tobacco dependence.
Who can have this medication?
As an adjunct to diet and exercise for the treatment of obese patients (BMI
30 kg/m2), or overweight patients (BMI > 27 kg/m2) with associated risk
factor(s), such as type 2 diabetes or dyslipidaemia ie. to start they must
have a BMI over 30. It can be 27 or over if they have diabetes [any form of
this] or high cholesterol.
Who cannot have this medication?
- ACOMPLIA should not be used in patients with severe hepatic impairment
- ACOMPLIA should not be used in patients with severe renal impairment
- ACOMPLIA is not recommended for use in children below age 18 due to a lack
of data on efficacy and safety
- Breast feeding mothers
- Anyone over 75 years old
- ACOMPLIA tablets contain lactose, patients with rare hereditary problems of
galactose intolerance, the Lapp lactase deficiency or glucose-galactose
malabsorption, should not take this medicine
- Therapy with rimonabant should not be initiated in patients with
uncontrolled serious psychiatric illness such as a major depression.
- Appropriate treatment of this condition should be initiated first and
therapy with rimonabant considered once this psychiatric condition is
controlled.
- As there is limited data in patients with antidepressant medication in
combination with rimonabant, use of rimonabant is not recommended in these
patients
- Patients who had a cardiovascular event (myocardial infarction, stroke,
etc.) less than 6 months ago were excluded in the studies for rimonabant and
so cannot be prescribed this medication
How much weight can you lose with Acomplia?
Most of the observed weight reduction was obtained within the first nine
months of treatment. ACOMPLIA 20 mg was effective in maintaining weight loss
up to two years.
Treatment with Acomplia was associated with significant reductions in waist
circumference, a known marker of intra-abdominal fat
So clients will not see immediate effects but can expect something within
the first 9 months.
They can take this medication for 2 years maximum
Should you switch from Xenical or Reductil to Acomplia?
If the other medications are working well, and with no side effects, it is
not necessary to switch to Acomplia.
How long do they have to wait to change from one drug to Acomplia?
If you want to switch from Xenical or Reductil to Acomplia, then you need
a week to clear the previous medication to then start taking Acomplia [if
switching from Acomplia to Reductil, we recommend 4 weeks inbetween]
How long do patients have to wait after stopping an antidepressive to
starting Acomplia?
We recommend 8 weeks.
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Each capsule contains 20mg Rimonabant
You can read more about this product by clicking here
to view Acomplia Patient information leaflet
If you have
any concerns or questions about whether or not you should take Acomplia
, talk to your healthcare provider.
IMPORTANT: It is very important that you make sure that your healthcare
provider knows what medications you take and what medical conditions and
allergies you have.
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